Aseptic fill and finish

We add value to your aseptic fill and finish manufacturing

Sever Pharma Solutions offers the solution for companies that need CMO capacity concerning the aseptic filling of syringes and assembly and packaging of pre-filled syringes and auto-injectors. We will enhance your product by adding value through manufacturing if you require short-term access to additional capacity or a complete technology transfer. We use single-use materials to prevent contamination and to ensure operators’ safety.

Sever Pharma Solutions’ aseptic fill and finish capabilities handling high-potent APIs include aseptic filling of syringes, made available in nests and tubs, ranging from 0,2 ml to 50 ml , testing and assembly of pre-filled syringes in auto-injectors. We handle compounding isolators, filling isolators, and solution handling from a disposable bag via single-use tubing.

State-of-the-art aseptic filling

Our capabilities within aseptic filling include a state-of-the-art automatic aseptic filling machine performed in an isolator of syringes, available in nests/tubs with an option of filling with nitrogen flushing during stoppering. We can handle filling 1 ml syringes, volumes of 0.2 – 50 ml. with a max capacity. 8,000 syringes/hour. We also provide you with:

  • Automatic particle measuring system.
  • System for air sampling.
  • Automatic fill weight control (% is flexible).

We perform testing by visual inspection and full analytical testing by an in-house analytical lab.

Sever Pharma Solutions offer assembly of pre-filled syringes in auto-injectors* and automated assembly into autoinjector devices. We have two manufacturing lines available with a capacity of max. 40 devices/minute. We offer secondary packing into multiple Stock Keeping Units (SKU) and serialization as an additional service.

*Other devices might require additional equipment.